Where do you place Evorel patches? One Evorel patch should be applied twice each week to a clean, dry, unbroken, non-irritated area of skin below the waist, on the lower back or buttocks. The patch should be worn continuously for three to four days and then replaced. How long after starting HRT Do you feel a difference? It usually takes a few weeks before you will feel the initial benefits of HRT and up to three months to feel the full effects. It may also take your body time to get used to HRT. When treatment begins you may experience side effects such as breast tenderness, nausea and leg cramps. Can I just stop taking hormone replacement therapy? Because of the link between using hormone replacement therapy (HRT) and increased breast cancer risk, HRT should be used at the lowest possible dose and for the shortest period of time possible to help manage menopausal symptoms. Stopping HRT can be done suddenly or gradually.
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